Reaction-free mitochondrial membrane potential independent luminogens with aggregation-induced emission characteristics for live neuron imaging

Hojeong Park, Guangle Niu, Alex Y.H. Wong, Eric Y. Yu, Ryan T.K. Kwok, Ben Zhong Tang*

*此作品的通讯作者

科研成果: 期刊稿件文章同行评审

摘要

We developed novel photostable mitochondria targeting probes based on aggregation-induced emission (AIE) luminogens with a cyanostilbene core. The introduction of an alkyl chain onto the pyridinium moiety enhanced their interaction with the mitochondrial membrane. This design effectively prevents probe leakage following mitochondrial membrane depolarization while significantly reducing cytotoxicity.

源语言英语
页(从-至)3536-3539
页数4
期刊Chemical Communications
61
17
DOI
出版状态已出版 - 30 1月 2025

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